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dc.rights.licensehttp://creativecommons.org/licenses/by/4.0/es_AR
dc.contributor.authorIbañez, Agustínes_AR
dc.contributor.authorUrquina, Diegoes_AR
dc.contributor.authorPetroni, Agustínes_AR
dc.contributor.authorBaez, Sandraes_AR
dc.contributor.authorLopez, Vladimires_AR
dc.contributor.authorNascimento, Micaela does_AR
dc.contributor.authorHerrera, Eduares_AR
dc.contributor.authorGuex, Raphaeles_AR
dc.contributor.authorHurtado, Estebanes_AR
dc.contributor.authorBlenkmann, Estebanes_AR
dc.contributor.authorBeltrachini, Leandroes_AR
dc.contributor.authorGelormini, Carloses_AR
dc.contributor.authorSigman, Marianoes_AR
dc.contributor.authorLischinsky, Aliciaes_AR
dc.contributor.authorTorralva, Teresaes_AR
dc.contributor.authorTorrente, Fernandoes_AR
dc.contributor.authorCetkovich, Marceloes_AR
dc.contributor.authorManes, Facundoes_AR
dc.date.accessioned2018-08-15T13:51:42Z
dc.date.available2018-08-15T13:51:42Z
dc.date.issued2012-10-08
dc.identifierdoi: 10.1371/journal.pone.0046877es_AR
dc.identifier.urihttps://doi.org/10.1371/journal.pone.0046877es_AR
dc.identifier.urihttps://repositorio.utdt.edu/handle/20.500.13098/11083
dc.description.abstractBackground: Adults with bipolar disorder (BD) have cognitive impairments that affect face processing and social cognition. However, it remains unknown whether these deficits in euthymic BD have impaired brain markers of emotional processing. Methodology/Principal Findings: We recruited twenty six participants, 13 controls subjects with an equal number of euthymic BD participants. We used an event-related potential (ERP) assessment of a dual valence task (DVT), in which faces (angry and happy), words (pleasant and unpleasant), and face-word simultaneous combinations are presented to test the effects of the stimulus type (face vs word) and valence (positive vs. negative). All participants received clinical, neuropsychological and social cognition evaluations. ERP analysis revealed that both groups showed N170 modulation of stimulus type effects (face . word). BD patients exhibited reduced and enhanced N170 to facial and semantic valence, respectively. The neural source estimation of N170 was a posterior section of the fusiform gyrus (FG), including the face fusiform area (FFA). Neural generators of N170 for faces (FG and FFA) were reduced in BD. In these patients, N170 modulation was associated with social cognition (theory of mind). Conclusions/Significance: This is the first report of euthymic BD exhibiting abnormal N170 emotional discrimination associated with theory of mind impairments.es_AR
dc.format.extent12 p.es_AR
dc.format.mediumapplication/pdfes_AR
dc.languageenges_AR
dc.relation.ispartofPLoS ONE 7(10):, (2012). ISSN: 1932-6203es_AR
dc.rightsinfo:eu-repo/semantics/openAccesses_AR
dc.subjectCaraes_AR
dc.subjectEmocioneses_AR
dc.subjectReconocimiento (Psicología)es_AR
dc.subjectTrastorno bipolares_AR
dc.subjectPotenciales evocadoses_AR
dc.subjectCogniciónes_AR
dc.subjectPruebas neuropsicológicases_AR
dc.titleNeural processing of emotional facial and semantic xxpressions in euthymic bipolar disorder (BD) and its association with theory of mind (ToM)es_AR
dc.typeinfo:eu-repo/semantics/articlees_AR
dc.subject.keywordFacees_AR
dc.subject.keywordEmotionses_AR
dc.subject.keywordFace recognitiones_AR
dc.subject.keywordBipolar disorderes_AR
dc.subject.keywordEvent-related potentialses_AR
dc.subject.keywordSocial cognitiones_AR
dc.subject.keywordCognitiones_AR
dc.subject.keywordNeurophsychological testinges_AR
dc.type.versioninfo:eu-repo/semantics/publishedVersiones_AR
dc.description.filiationFil: Ibañez, Agustín. Laboratory of Experimental Psychology and Neuroscience, Institute of Cognitive Neurology and Institute of Neuroscience, Favaloro University, Buenos Aires, Argentina. National Scientific and Technical Research Council, Buenos Aires, Argentina. Universidad Diego Portales, Santiago, Chilees_AR
dc.description.filiationFil: Urquina, Diego. Laboratory of Experimental Psychology and Neuroscience, Institute of Cognitive Neurology and Institute of Neuroscience, Favaloro University, Buenos Aires, Argentina. Grupo de Investigacio´n Neurored, Universidad Surcolombiana, Neiva, Colombiaes_AR
dc.description.filiationFil: Petroni, Agustín. National Scientific and Technical Research Council, Buenos Aires, Argentina. Integrative Neuroscience Laboratory, Physics Department, University of Buenos Aires, Buenos Aires, Argentinaes_AR
dc.description.filiationFil: Baez, Sandra. Laboratory of Experimental Psychology and Neuroscience, Institute of Cognitive Neurology and Institute of Neuroscience, Favaloro University, Buenos Aires, Argentina. National Scientific and Technical Research Council, Buenos Aires, Argentina. Pontificia Universidad Cato´ lica Argentina, Buenos Aires, Argentinaes_AR
dc.description.filiationFil: Lopez, Vladimir. Pontificia Universidad Católica de Chile, Santiago, Chilees_AR
dc.description.filiationFil: Nascimento, Micaela do. Laboratory of Experimental Psychology and Neuroscience, Institute of Cognitive Neurology and Institute of Neuroscience, Favaloro University, Buenos Aires, Argentinaes_AR
dc.description.filiationFil: Herrera, Eduar. Universidad Autónoma del Caribe, Barranquilla, Colombiaes_AR
dc.description.filiationFil: Guex, Raphael. Laboratory for Behavioral Neurology and Imaging of Cognition, University of Geneva, Geneva, Switzerlandes_AR
dc.description.filiationFil: Hurtado, Esteban. Pontificia Universidad Católica de Chile, Santiago, Chilees_AR
dc.description.filiationFil: Blenkmann, Esteban. National Scientific and Technical Research Council, Buenos Aires, Argentina. Epilepsy Center, University of Buenos Aires – National Scientific and Technical Research Council – University of Buenos Aires, Buenos Aires, Argentina. Laboratory of Industrial Electronics, Control and Instrumentation, National University of La Plata, La Plata, Argentinaes_AR
dc.description.filiationFil: Beltrachini, Leandro. National Scientific and Technical Research Council, Buenos Aires, Argentina. Laboratory of Industrial Electronics, Control and Instrumentation, National University of La Plata, La Plata, Argentinaes_AR
dc.description.filiationFil: Gelormini, Carlos. Laboratory of Experimental Psychology and Neuroscience, Institute of Cognitive Neurology and Institute of Neuroscience, Favaloro University, Buenos Aires, Argentina. National Scientific and Technical Research Council, Buenos Aires, Argentinaes_AR
dc.description.filiationFil: Sigman, Mariano. National Scientific and Technical Research Council, Buenos Aires, Argentina. Universidad Torcuato Di Tella, Escuela de Negocios, Laboratorio de Neurociencia, Buenos Aires, Argentinaes_AR
dc.description.filiationFil: Lischinsky, Alicia. Laboratory of Experimental Psychology and Neuroscience, Institute of Cognitive Neurology and Institute of Neuroscience, Favaloro University, Buenos Aires, Argentinaes_AR
dc.description.filiationFil: Torralva, Teresa. Laboratory of Experimental Psychology and Neuroscience, Institute of Cognitive Neurology and Institute of Neuroscience, Favaloro University, Buenos Aires, Argentinaes_AR
dc.description.filiationFil: Torrente, Fernando. Laboratory of Experimental Psychology and Neuroscience, Institute of Cognitive Neurology and Institute of Neuroscience, Favaloro University, Buenos Aires, Argentinaes_AR
dc.description.filiationFil: Cetkovich, Marcelo. Laboratory of Experimental Psychology and Neuroscience, Institute of Cognitive Neurology and Institute of Neuroscience, Favaloro University, Buenos Aires, Argentinaes_AR
dc.description.filiationFil: Manes, Facundo. Laboratory of Experimental Psychology and Neuroscience, Institute of Cognitive Neurology and Institute of Neuroscience, Favaloro University, Buenos Aires, Argentinaes_AR


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